collagenase clostridium histolyticum
Cold Chain RequiredFDA Approved
Description
Collagenase clostridium histolyticum is an enzymatic treatment that breaks down collagen in fibrotic tissue. While primarily approved for Dupuytren's contracture and Peyronie's disease, it has been investigated for use in dermal cysts and fibrotic skin lesions. The enzyme selectively degrades collagen types I and III found in pathological connective tissue.
Indications & Therapeutic Use
Dupuytren's contracture, Peyronie's disease, dermal cysts
Global Availability (2 countries)
| Country | Access Route | Regulatory Pathway | Lead Time | Status |
|---|---|---|---|---|
| — | — | — | — | |
| — | — | — | — |
Available Through
This drug is available for procurement through the following fulfilment partner.
Fulfilment Partner
collagenase clostridium histolyticum
| Generic Name | collagenase clostridium histolyticum |
| Brands | 1 brand available |
| Active Ingredient | collagenase clostridium histolyticum |
| Drug Class | Dupuytren's contracture |
| Manufacturer | Endo Pharmaceuticals |
| Dosage Forms | injection, 0.9mg lyophilized powder for reconstitution |
| Medical Code | M09AB02 |
| Orphan Status | No |
| Cold Chain | Required |
| Lead Time | 21 days |
| Reg. Status | FDA Approved |
| Clinical Trial | NCT00528606 |
| Countries | 2 countries |
Authority Signals
Last Verified3/21/2026
Data ConfidenceHigh (AI + Pharmacist)
Source Citations3 Validated Nodes