Collagenase clostridium histolyticum

Cold Chain RequiredFDA Approved

Description

Collagenase clostridium histolyticum is an enzymatic treatment that breaks down collagen in fibrotic tissue. While primarily approved for Dupuytren's contracture and Peyronie's disease, it has been investigated for use in dermal cysts and fibrotic skin lesions. The enzyme selectively degrades collagen types I and III found in pathological connective tissue.

Indications & Therapeutic Use

Dupuytren's contracture, Peyronie's disease, dermal cysts

Global Availability (2 countries)

CountryAccess RouteRegulatory PathwayLead TimeStatus

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Available Through

This drug is available for procurement through the following fulfilment partner.

Fulfilment Partner
Collagenase clostridium histolyticum
Generic Namecollagenase clostridium histolyticum
Brands1 brand available
Active Ingredientcollagenase clostridium histolyticum
Drug ClassDupuytren's contracture
ManufacturerEndo Pharmaceuticals
Dosage Formsinjection, 0.9mg lyophilized powder for reconstitution
Medical CodeM09AB02
Orphan StatusNo
Cold ChainRequired
Lead Time21 days
Reg. StatusFDA Approved
Clinical TrialNCT00528606
Countries2 countries
Authority Signals
Last Verified3/21/2026
Data ConfidenceHigh (AI + Pharmacist)
Source Citations3 Validated Nodes