Olipudase alfa

Orphan Drug Cold Chain RequiredFDA Approved

Description

Olipudase alfa is a recombinant human acid sphingomyelinase (ASM) enzyme. It is indicated for the treatment of non-central nervous system (CNS) manifestations of acid sphingomyelinase deficiency (ASMD), also known as Niemann-Pick disease type A/B and type B.

Indications & Therapeutic Use

Acid Sphingomyelinase Deficiency (ASMD)

Global Availability (2 countries)

CountryAccess RouteRegulatory PathwayLead TimeStatus

Available Through

This drug is available for procurement through the following fulfilment partner.

Fulfilment Partner
Olipudase alfa
Generic NameOlipudase alfa
Brands1 brand available
Active IngredientOlipudase alfa
Drug ClassAcid Sphingomyelinase Deficiency (ASMD)
ManufacturerSanofi Genzyme
Dosage FormsLyophilized powder for IV infusion
Medical CodeA16AB14
Orphan StatusYes — Orphan Drug
Cold ChainRequired
Lead Time14 days
Reg. StatusFDA Approved
Clinical TrialNCT02004695
Countries2 countries
Authority Signals
Last Verified3/21/2026
Data ConfidenceHigh (AI + Pharmacist)
Source Citations3 Validated Nodes