Article 83 Compassionate Use – South Africa (SAHPRA)

SAHPRA Section 21 Application FormStatutory30 days

Description & Eligibility

Section 21 authorization allows for the sale of unregistered medicines in South Africa for compassionate use in individual patients or clinical trials. SAHPRA evaluates applications based on medical necessity and patient safety considerations.

Eligibility Criteria

Patients with life-threatening or seriously debilitating conditions where no registered alternative exists in South Africa

Legal Reference / Source

Medicines and Related Substances Act 101 of 1965, Section 21

Article 83 Compassionate Use – South Africa (SAHPRA)
Approval FormSAHPRA Section 21 Application Form
Timeline30 days
Legal StatusStatutory
Source Ref.Medicines and Related Substances Act 101 of 1965, Section 21
Countries0 countries
Compliance Check
Legal Review3/21/2026
Global ValidityVerified