ALG1-CDG

ORPHA: 793271 Treatment Available

Overview

medical condition

Available Treatments (1)

DrugFormStatusCountriesLead Time
mannose
Orphan
Oral powder for solution; Oral capsule 500mgInvestigational614d

Clinical Presentation

Signs and symptoms associated with ALG1-CDG, sourced from HPO and Orphanet clinical annotations.

Intellectual disabilitySeizureHypotoniaGlobal developmental delayProgressive microcephalyAbnormality of the eyeStrabismusAbnormality of the skeletal systemMild intellectual disabilityAbnormality of blood and blood-forming tissuesAbnormal facial shapeChronic diarrheaScoliosisHypoalbuminemiaAbnormality of the gastrointestinal tractSevere global developmental delayBrain imaging abnormalityAbnormality of the kidneyRenal insufficiencyNephrotic syndromeNystagmusCerebellar atrophyLimitation of joint mobilityDecreased liver functionAbnormal heart morphologyCardiomyopathyCerebral atrophyProtein-losing enteropathyRecurrent infectionsImmunodeficiencyKyphosisRespiratory failureSepsis

Classification & Codes

Orphanet Code

ORPHA:79327
ALG1-CDG
OrphanetORPHA:79327
Treatments1 drug(s)
Symptoms on record33 signs
Statuspublished

Treatment Summary

Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO