Femoral-facial syndrome

MeSH: C537916ORPHA: 19881 Treatment Available

Overview

Femoral-facial syndrome is characterized by predominant femoral hypoplasia (bilateral or unilateral) and unusual facies

Available Treatments (1)

DrugFormStatusCountriesLead Time
Growth hormone (somatropin)
Orphan Cold Chain
Subcutaneous injection, 5mg, 12mg cartridgesFDA Approved814d

Clinical Presentation

Signs and symptoms associated with Femoral-facial syndrome, sourced from HPO and Orphanet clinical annotations.

Cleft palateMicrognathiaShort femurOrofacial cleftThin upper lip vermilionLong philtrumLow-set earsUpslanted palpebral fissureHip dysplasiaTalipes equinovarusPreaxial foot polydactylyAbnormal pelvic girdle bone morphologyCoxa varaAbnormal fibula morphologyShort noseVertebral segmentation defectShort statureAbnormal sacrum morphologyAplasia/Hypoplasia of the tibiaMicrotiaInguinal herniaCryptorchidismLong penisPolycystic kidney dysplasiaStrabismusAbnormal rib morphologyRib fusionSprengel anomalyVentriculomegalyScoliosisRadioulnar synostosisAplasia/Hypoplasia of the corpus callosumRenal hypoplasia/aplasiaAbnormal cardiovascular system morphologyAbnormal localization of kidney

Classification & Codes

MeSH Code

C537916

Orphanet Code

ORPHA:1988
Femoral-facial syndrome
MeSHC537916
OrphanetORPHA:1988
Treatments1 drug(s)
Symptoms on record35 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO