otofaciocervical syndrome

ORPHA: 27923 Treatments Available

Overview

medical condition

Available Treatments (3)

DrugFormStatusCountriesLead Time
Growth hormone (somatropin)
Orphan Cold Chain
Subcutaneous injection, 5mg, 12mg cartridgesFDA Approved814d
Multivitamin with Calcium and Vitamin D
Oral tablets, chewable tablets, liquid suspensionOTC - Multiple jurisdictions91d
Occupational and Physical Therapy Support
Therapeutic sessions, adaptive devices, orthoticsStandard of Care914d

Clinical Presentation

Signs and symptoms associated with otofaciocervical syndrome, sourced from HPO and Orphanet clinical annotations.

High palateFull cheeksFacial asymmetryMacrotiaConductive hearing impairmentProtruding earAtresia of the external auditory canalAnteverted naresAbnormal clavicle morphologyIntellectual disabilityGlobal developmental delayHypertoniaHyperreflexiaAbnormal speech patternDelayed skeletal maturationScapular wingingShort staturePreauricular pitDepressed nasal bridgeAbnormal dermatoglyphicsRenal hypoplasia/aplasiaAbnormal antihelix morphologyDown-sloping shoulders

Classification & Codes

Orphanet Code

ORPHA:2792
otofaciocervical syndrome
OrphanetORPHA:2792
Treatments3 drug(s)
Symptoms on record23 signs
Statuspublished
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO