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short stature-advanced bone age-early-onset osteoarthritis syndrome

ORPHA: 4358042 Treatments Available

Contents

  1. 1. Overview
  2. 2. Available Treatments
  3. 3. Clinical Presentation
  4. 4. Classification & Codes

Overview

human disease

Available Treatments (2)

DrugFormStatusCountriesLead Time
Growth hormone (somatropin)
Orphan Cold Chain
Subcutaneous injection, 5mg, 12mg cartridgesFDA Approved814d
Bisphosphonates (pamidronate)
IV infusion 30mg, 60mg, 90mg vialsFDA Approved610d

Clinical Presentation

Signs and symptoms associated with short stature-advanced bone age-early-onset osteoarthritis syndrome, sourced from HPO and Orphanet clinical annotations.

BrachydactylyDevelopmental stagnationShort thumbMidface retrusionOsteoarthritis

Classification & Codes

Orphanet Code

ORPHA:435804
short stature-advanced bone age-early-onset osteoarthritis syndrome
OrphanetORPHA:435804
Treatments2 drug(s)
Symptoms on record5 signs
Statuspublished

Treatment Summary

Growth hormone (somatropin)· OrphanBisphosphonates (pamidronate)
Factual Authority
Last Updated3/20/2026
Clinical DataHPO · Orphanet
Drug DataFDA · EMA · CDSCO