temozolomide

Orphan DrugFDA Approved, EMA Approved

Description

Temozolomide is an oral alkylating agent used in the treatment of brain tumors including glioblastoma multiforme and anaplastic astrocytoma. It is also used for certain pediatric brain tumors and embryonal tumors of the central nervous system. The drug methylates DNA, leading to cell death in rapidly dividing cancer cells.

Indications & Therapeutic Use

glioblastoma multiforme, anaplastic astrocytoma, embryonal brain tumors, medulloblastoma

Global Availability (10 countries)

CountryAccess RouteRegulatory PathwayLead TimeStatus

Available Through

This drug is available for procurement through the following fulfilment partner.

temozolomide
Generic Nametemozolomide
Brands1 brand available
Active Ingredienttemozolomide
Drug Classglioblastoma multiforme
ManufacturerMerck/Sun Pharmaceutical
Dosage Formsoral capsule, 5 mg, 20 mg, 100 mg, 140 mg, 180 mg, 250 mg
Medical CodeL01AX03
Orphan StatusYes — Orphan Drug
Cold ChainNot Required
Lead Time7 days
Reg. StatusFDA Approved, EMA Approved
Clinical TrialNCT00002840
Countries10 countries
Authority Signals
Last Verified3/21/2026
Data ConfidenceHigh (AI + Pharmacist)
Source Citations11 Validated Nodes